Programming and regulation of metabolic homeostasis.

مقایسه سطح خونی هورمون لپتین در بیماران چاق دیابتی و غیردیابتی

Introduction: Leptin was first discovered from the "Ob Gene" by Friedwan and co-workers in 1994. It is a small peptide with 167 amino acids and molecular weight of 16 Kd . It is secreted by adipose tissues. Leptin has two type of receptors in Hypothalamus and other tissues including muscles, liver and intestines. Leptin inhibits neuropeptide Y resulting in decreased appetite and on the other ha...

Comparison of Waist Circumference and Metabolic Syndrome as a Prognostic Value of Insulin Resistance in Elderly Residents of Kahrizak

Objectives: The aim of this study was to compare of waist circumference with metabolic syndrome ,as a predictor insulin resistance in agroup of elderly population. Methods & Materials: In a cross-sectional study among 225 elderlyaged 60 year old and more whose clinical data were complete, 94 subjects (42 males and 52 females) who were able to sign the consent form Mini Mental stat Examinatio...

REGULATION OF ACID-BASE HOMEOSTASIS BY THE KIDNEY

Breast Milk Hormones and Regulation of Glucose Homeostasis

Growing evidence suggests that a complex relationship exists between the central nervous system and peripheral organs involved in energy homeostasis. It consists in the balance between food intake and energy expenditure and includes the regulation of nutrient levels in storage organs, as well as in blood, in particular blood glucose. Therefore, food intake, energy expenditure, and glucose homeo...

Interface between Nutrition and Reproduction: the Very Basis of Production

Contents 1. Introduction: Interface between nutrition, reproduction and animal production 2. Basic aspects on intermediary metabolism: Hormonal control of energy homeostasis 3. Basic aspects of reproduction: Neuroendocrine regulation 4. Integration of nutrition and reproduction: Neuroendocrine mechanisms 5. Direct roles of nutrition in modulating reproductive function 6. The Kiss1 system: Novel...

HORSE SPECIES SYMPOSIUM: Glucocorticoid programming of hypothalamic-pituitary-adrenal axis and metabolic function: Animal studies from mouse to horse.

Adrenal glucocorticoids, such as cortisol, are essential for normal fetal development and for maintaining homeostasis in adults. Developmental studies in humans and other animals have shown that exposure to excess glucocorticoids during critical windows of perinatal development can program permanent changes in hypothalamic-pituitary-adrenal (HPA) axis function and metabolic function, with adver...